F120 Inhibitory effect of a new non-steroidal pure antiestrogen (EM-800) in combination with DHEA on human ZR-75-1 breast tumors in nude mice

Effect of treatment sequence with radiot

Effect of treatment sequence with radiotherapy and the antiestrogen EM 800 on the growth of ZR 75 1 human mammary carcinoma in nude mice

✍ Mathieu Gutman; Steeve Couillard; Fernand Labrie; Bernard Candas; Claude Labrie 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 153 KB

## Abstract We demonstrated previously that continuous administration of EM‐800, a SERM having pure antiestrogenic activity in the mammary gland and endometrium in combination with monthly radiotherapy caused a greater inhibition of human ZR 75 1 tumor growth in nude mice than either therapy used a