Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear

Transforming growth factor-β1 signaling

Transforming growth factor-β1 signaling participates in the physiological and pathological regulation of mouse inner ear development by all-trans retinoic acid

✍ Sydney C. Butts; Wei Liu; Geming Li; Dorothy A. Frenz 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 481 KB 👁 1 views

BACKGROUND: Retinoic acid (RA) is a vitamin A derivative that participates in patterning and regulation of inner ear development. Either excess RA or RA deficiency during a critical stage of inner ear development can produce teratogenic effects. Previous studies have shown that in utero exposure of