𝔖 Bobbio Scriptorium
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Extraskeletal osteogenic sarcoma. A Late Complication of Radiation Therapy

✍ Scribed by Carl W. Boyer Jr.; James J. Navin


Publisher
John Wiley and Sons
Year
1965
Tongue
English
Weight
681 KB
Volume
18
Category
Article
ISSN
0008-543X

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✦ Synopsis


T ation is well documented. T h e first case of radiation-induced cancer in man was published in 1902, 7 years after the discovery of X-rays.3 This case report soon was followed by others. T h e classic picture was that of a squamous-cell carcinoma arising in an area of chronic radiodermatitis. Sarcomatous changes in the soft tissues are rare and it is recognized that a significant proportion of the early reported cases of this entity were actually spindle-cell epitheliomata. Moreover, cases with true sarcomatous change may be quite difficult to differentiate from the more benign fibroblastic tumors of the dermis (pseudosarcoma).z* 7, T h e appearance of extraskeletal osteogenic sarcoma in an irradiated field is practically unheard of. There are only 2 caseslp 6 to be found in the literature. A third case was observed recently by the authors and is similar in clinical course to the first case reported by Auerbach et al.1 in 1951. Shortly after this patient was admitted to the hospital another case was discovered during a follow-up study of the 47 testicular tumors seen and treated at Tripler General Hospital since 1952. Our surprise at the sudden doubling of the number of cases of an extremely rare occurrence prompted this case report (Table ).

CASE REPORTS

Case 1. This 29-year-old naval officer was found to have an enlarged right testicle during a routine annual physical examination in March 1959. He was hospitalized and on April 30, 1959 a right orchiectomy was performed and a histologic diagnosis of seminoma was made from the specimen (Fig. ). On May 11,


πŸ“œ SIMILAR VOLUMES


Retroperitoneal soft tissue sarcomas: A
✍ BussiΓ¨res, Emmanuel; StΓΆckle, Eberhard P.; Richaud, Pierre M.; Avril, Antoine R. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 709 KB

This pilot study was conducted to evaluate the feasibility and tolerance of a multimodal therapy of retroperitoneal soft tissue sarcoma (STS), including intraoperative radiation therapy (IORT). Nineteen patients (14 primarily treated patients and 5 treated for a recurrent tumor) were included. Surge