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Extraosseous localization of99mTc-MDP in ganglioneuroblastoma

✍ Scribed by Wei-Jen Shih; Frank H. DeLand; Peggy A. Domstad; Edward H. Johnston

Publisher: Springer
Year: 1982
Tongue: English
Weight: 325 KB
Volume: 7
Category: Article
ISSN: 0340-6997
DOI: 10.1007/bf00253434

No coin nor oath required. For personal study only.

✦ Synopsis

A 2 1/2-year-old boy with a posterior mediastinal ganglioneuroblastoma was evaluated by bone scintigraphy using 99mTc-DMP and showed a marked increased uptake in the tumor mass. Although a routine chest X-ray and body CT scan failed to demonstrate calcification, X-ray examination of the removed tumor specimen revealed small scattered calcification. The proposed mechanisms of the radiopharmaceutical localization in benign and malignant tumors other than calcification/mineralization are discussed. Regardless of the mechanism, localization of a bone scanning agent in a tumor provides a rapid, simple, and noninvasive means of demonstrating tumor size, configuration, and the relation of the surrounding structures to the tumor.

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