Multipotential neuroepithelial stem cells are thought to give rise to all the differentiated cells of the central nervous system (CNS). The developmental potential of these multipotent stem cells becomes more restricted as they differentiate into progressively more committed cells and ultimately int
Extramedullary blast transformation in the central nervous system in idiopathic myelofibrosis
โ Scribed by Harry M. Barnes; Josef T. Prchal; C. W. Scott
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 300 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0361-8609
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Idiopathic granulomatous angiitis of the central nervous system (IGANS) is a rare vasculitis primarily affecting the spinal cord and brain not related to any underlying systemic disease. Clinical manifestations range from simple headache to cerebral vascular accidents secondary to vascular occlusion
Acquisition of cell type-specific properties in the nervous system is likely a process of sequential restriction in developmental potential. At least two classes of pluripotent stem cells, neuroepithelial (NEP) stem cells and EGF-dependent neurosphere stem cells, have been identified in distinct spa