Extramammary Paget’s disease in two siblings
✍ Scribed by T. Demitsu; K. Gonda; M. Tanita; K. Takahira; T. Inoue; O. Okada; K. Yoneda; M. Manabe
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 171 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0007-0963
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## Abstract We describe two Japanese female patients with pigmented extramammary Paget’s disease (EMPD); one patient had a dark brown plaque and the other had a reddish patch with a pigmented area, both affecting the vulval region. Histochemical and immunohistochemical examinations confirmed EMPD w
Ten genital skin specimens, biopsy proven to be Paget's disease, were examined by human papillomavirus (HPV) in situ hybridization in an effort to detect DNA of HPV types 6, 11, 16, 18, 31, 33, and 35. All ten specimens showed no evidence of DNA of these HPV types. Extramammary Paget's disease is pr