Extraction of sulfones with 2-nitro-1-propanol
✍ Scribed by L. M. Kozlov; I. N. Diyarov; V. G. Kozin; N. A. Lutfullina; N. I. Diyarova
- Publisher
- Springer US
- Year
- 1978
- Tongue
- English
- Weight
- 273 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0009-3092
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📜 SIMILAR VOLUMES
A short, efficient synthesis for 1-(2-[180 2 ] -n i t r o -1 -i m i d a z o l y l ) -3methoxy-2-propanol ( [ I 8 0 2] -misonidazole) from 2-aminoimidazole is described. The required 180-labeled sodium nitrite (82.6 atom %) was conveiently synthesized by the treatment of sodium nitrite with DOWEX SOW
In the title compound, C~28~H~22~BrN~3~O~5~S·0.5C~4~H~10~O, the tetrahydropyrazine ring adopts a distorted half-chair conformation. The bromobenzaldehyde substituent has an axial orientation, while the 4-nitrophenyl group is in an equatorial position. The benzene rings of these substituents are not