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Extraction of an actin-like protein from the plasmodium of a myxomycete and its interaction with myosin a from rabbit striated muscle

✍ Scribed by Sadashi Hatano; Fumio Oosawa


Publisher
John Wiley and Sons
Year
1966
Tongue
English
Weight
466 KB
Volume
68
Category
Article
ISSN
0021-9541

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✦ Synopsis


An actin-like protein was obtained from the plasmodia of a myxomycete, Physarum polycephalum. It forms a complex with muscle myosin A which behaves similarly to the actomyosin from rabbit striated muscle. On the addition of ATP the complex of this protein with myosin A shows a viscosity drop at high concentrations of KC1 (-0.5 M). At low concentrations of KC1 (+ 0.05 M) this com- plex superprecipitates from solutions containing 1 mM MgClz and shows Mg-activated ATPase activity. That is, the actin-like protein converts the ATPase of mvosin A to the actomyosin type.