𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Extractable herpesvirus antigens from chickens with marek's disease

✍ Scribed by Mumtaz Ahmed; Judith B. Leech; Susan M. Slattery; George Schidlovsky

Book ID
102864578
Publisher
John Wiley and Sons
Year
1971
Tongue
French
Weight
630 KB
Volume
7
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Marek's disease herpesvirus (MDHV) antigens are demonstrable by indirect immunofluorescence and micro‐immunodiffusion tests in epithelial cells of feather follicles (FF) of chickens infected with GA strain of MDHV; but lymphoid tumor cells are devoid of virus particles and virus‐associated antigens. The antigens extracted from virus‐containing epithelial cells growing in vivo or in vitro were found to be of a similar nature. Electron microscopy showed that antibody‐positive chicken sera caused specific coating of MDHV particles extracted from feather follicular cells.

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✍ F. Lesnik; L. J. N. Ross 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 642 KB

## Abstract Immunity against Marek's disease was conferred by the use of non‐infectious materials extracted with non‐ionic detergents from cells infected with the attenuated strain of Marek's disease virus (MDV). Antibody‐free Rhode Island Red chicks were inoculated at 1 week of age with cell extra