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Extracellular transglutaminase 2 activates β-catenin signaling in calcifying vascular smooth muscle cells

✍ Scribed by Lidia Faverman; Lyudmila Mikhaylova; Jennifer Malmquist; Maria Nurminskaya

Book ID
113620737
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
467 KB
Volume
582
Category
Article
ISSN
0014-5793

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## Abstract Although the pivotal role of platelet derived growth factor (PDGF)‐mediated signaling in vascular diseases was demonstrated, the pathophysiological mechanisms driving its over‐activation remain incompletely understood. Tissue transglutaminase (tTG) is a multifunctional protein expressed