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Extracellular Superoxide Dismutase Overexpression Protects Against Aging-Induced Cognitive Impairment in Mice

✍ Scribed by Edward D. Levin; N. Channelle Christopher; Sohail Lateef; Belal M. Elamir; Manisha Patel; Li-Ping Liang; James D. Crapo

Book ID
110334407
Publisher
Springer US
Year
2002
Tongue
English
Weight
66 KB
Volume
32
Category
Article
ISSN
0001-8244

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Our previous study demonstrated that polycationic liposomes are highly stable in the bloodstream and represent an effective agent for liver gene delivery. We report here that liposomemediated extracellular superoxide dismutase (EC-SOD) gene delivery successfully prevented acute liver injury in mice.