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Extracellular-signal-regulated kinase signalling in neurons

✍ Scribed by Savraj S Grewal; Randall D York; Philip JS Stork

Book ID
114314134
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
130 KB
Volume
9
Category
Article
ISSN
0959-4388

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## Abstract 17‐β‐Estradiol (E2) stimulates the growth of axons in male‐derived hypothalamic neurons in vitro. This effect is not exerted through the classical intracellular estrogen receptor (ER) but depends on a membrane mechanism involving TrkB. In the present study, we investigate the intracellu