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Extracellular-regulated kinase controls β-amyloid precursor protein mRNA decay

✍ Scribed by Cara J Westmark; James S Malter


Book ID
117385690
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
782 KB
Volume
90
Category
Article
ISSN
0169-328X

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We have studied the influence of the extracellular matrix (ECM) on the amount of beta-amyloid precursor protein (APP) and C-terminal amyloid-bearing fragments in 313 fibroblasts. After incubation with ECM components, the cellular APP content of 3T3 cells changed. Besides, different substrata includi