Mechanism of extracellular ubiquitinatio
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Kathleen M. Baska; Gaurishankar Manandhar; Dawn Feng; Yuksel Agca; Mark W. Tengo
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Article
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2008
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John Wiley and Sons
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English
β 653 KB
## Abstract Posttranslational modification by ubiquitination marks defective or outlived intracellular proteins for proteolytic degradation by the 26S proteasome. The ATPβdependent, covalent ligation and formation of polyubiquitin chains on substrate proteins requires the presence and activity of a