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Extracellular Purines Promote the Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells to the Osteogenic and Adipogenic Lineages

✍ Scribed by Ciciarello, Marilena; Zini, Roberta; Rossi, Lara; Salvestrini, Valentina; Ferrari, Davide; Manfredini, Rossella; Lemoli, Roberto M.


Book ID
120448390
Publisher
Mary Ann Liebert
Year
2013
Tongue
English
Weight
652 KB
Volume
22
Category
Article
ISSN
1547-3287

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## Abstract AMP‐activated protein kinase (AMPK) is an energy‐sensing kinase that has recently been shown to regulate the differentiation of preadipocytes and osteoblasts. However, the role of AMPK in stem cell differentiation is largely unknown. Using in vitro culture models, the present study demo