Extracellular potassium regulates the chloride reversal potential in cultured hippocampal neurons
β Scribed by Trevor Balena; Brooke A. Acton; Dmitrii Koval; Melanie A. Woodin
- Book ID
- 113503387
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 546 KB
- Volume
- 1205
- Category
- Article
- ISSN
- 0006-8993
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Chloride currents were activated by a low concentration of GABA (0.5 microM) in neonatal rat hippocampal neurons cultured for up to 14 days. Currents elicited by 0.5 microM GABA in neurons, voltage-clamped using the whole-cell technique with pipettes containing 149 mM Cl-, reversed close to 0 mV whe
## Abstract Neuroserpin is a member of the serpin superfamily that is expressed principally in neurons of the central and peripheral nervous systems. Neuroserpin's spatialβtemporal expression during development and in the adult brain suggests possible roles in synaptogenesis and synaptic plasticity