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Extracellular matrix contraction by cultured mesangial cells: Modulation by transforming growth factor-β and matrix components

✍ Scribed by Masanori Kitamura; Naoki Maruyama; Tetsuya Mitarai; Ryuji Nagasawa; Hiroaki Yoshida; Osamu Sakai

Book ID
113147488
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
879 KB
Volume
56
Category
Article
ISSN
0014-4800

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✍ Gouri Shanker; Dan Olson; Roger Bone; Rajinder Sawhney 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 372 KB

Transforming growth factor beta-1 (TGF-1 ), which is present in lung tissue, has been suggested to play a role in modulating vascular cell function in vivo. The action of TGF-1 in vivo, especially at the local site of application to connective tissue, is anabolic and leads to pulmonary fibrosis and