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Extracellular HIV-1 Nef protein modulates lytic activity and proliferation of human CD8+ T lymphocytes

✍ Scribed by G. Gómez-Icazbalceta; L. Huerta; L.E. Soto-Ramirez; C. Larralde


Book ID
113527096
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
188 KB
Volume
250
Category
Article
ISSN
0008-8749

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## Abstract IL‐27 has been shown to exhibit both pro‐ and anti‐inflammatory properties; it favors mouse naïve CD4^+^T‐cell differentiation into Th1 cells to the detriment of Th17 and Th2 skewing and regulates IL‐10 and IL‐17 production by human CD4^+^ T cells. Moreover, IL‐27 promotes proliferation