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Extracellular fluid S100B in the injured brain: a future surrogate marker of acute brain injury?

✍ Scribed by J. Sen; A. Belli; A. Petzold; S. Russo; G. Keir; E. J. Thompson; M. Smith; N. Kitchen

Publisher
Springer Vienna
Year
2005
Tongue
English
Weight
189 KB
Volume
147
Category
Article
ISSN
0001-6268

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## Abstract The aim of this study was to evaluate the screening and diagnostic validity of the initial serum S100 levels by Elecsys S100 immunoassay in an emergency department. We measured serum S100 in 101 acute brain injury (ABI) patients, in 40 healthy subjects, and in 41 chronic brain injury (C

Secondary insults following traumatic br
Secondary insults following traumatic brain injury enhance complement activation in the human brain and release of the tissue damage marker S100B
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## Object Complement activation has been suggested to play a role in the development of secondary injuries following traumatic brain injury (TBI). The present study was initiated in order to analyze complement activation in relation to the primary brain injury and to secondary insults, frequently o