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Extracellular cAMP formation from host cell ATP by Bordetella pertussis adenylate cyclase

โœ Scribed by Fabrizio Gentile; Anastassios Raptis; Leslie G. Knipling; J. Wolff


Book ID
117046837
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
612 KB
Volume
971
Category
Article
ISSN
0005-2728

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โœ Maura G. Donovan; Daniel R. Storm ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 545 KB

## Abstract Bordetella pertussis, the pathogen responsible for whooping cough, produces a calmodulinโ€sensitive adenylate cyclase. Several investigators have shown that the partially purified adenylate cyclase is capable of entering animal cells and elevating intracellular cAMP levels (Confer and Ea