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Extracellular cAMP-dependent protein kinase (ECPKA) in melanoma

✍ Scribed by Tsunekazu Kita; James Goydos; Elena Reitman; Roald Ravatn; Yong Lin; Wei-Chung Shih; Yoshihiro Kikuchi; Khew-Voon Chin

Book ID
116333087
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
150 KB
Volume
208
Category
Article
ISSN
0304-3835

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The CAMP-dependent protein kinase (cAK) from Diciyosteliurn discoideurn is an enzyme composed of one catalytic and one regulatory subunit. Upon binding of CAMP, the holoenzyme dissociates to liberate free active catalytic subunits. The cAK is developmentally regulated, ranging from very little activ