Extracellular calcium and the inotropic effect of cooling on isolated skeletal muscle
β Scribed by William S. Barnes
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 648 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0306-4565
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The purpose of this investigation was to determine the effects of low extracellular calcium and calcium antagonists on skeletal muscle staircase and fatigue. Initial experiments revealed that, brief exposure (1 0 minutes) of single frog sartorius muscle to diltiazem, D-600 (5 and 30 pM) and low calc
## Abstract A dual effect of external Ca^2+^ on creatine kinase (CPK) accumulation during myogenesis has recently been demonstrated (Morris and Cole, '79). Ca^2+^ inhibits muscleβspecific CPK accumulation at intermediate (50β100 ΞΌ) concentrations compared with both lower (no added Ca^2+^) and highe