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Extracellular Ca2+ sensing by the osteoclast

โœ Scribed by M. Zaidi; A.S.M.T. Alam; C.L.-H. Huang; M. Pazianas; C.M.R. Bax; B.E. Bax; B.S. Moonga; P.J.R. Bevis; V.S. Shankar


Book ID
113236630
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
760 KB
Volume
14
Category
Article
ISSN
0143-4160

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Ionic channels regulated by extracellular Ca2+ concentration ([Ca"],) were examined in freshly isolated rabbit osteoclasts. K+ current was suppressed by intracellular and extracellular Cs' ions. In this condition, high [Ca2+lo evoked an outwardly rectifying current with a reversal potential of about