Parkin potentiates ATP-induced currents
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Ayumi Sato; Yukiko Arimura; Yoshimasa Manago; Kaori Nishikawa; Kumiko Aoki; Etsu
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Article
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2006
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John Wiley and Sons
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English
⚖ 470 KB
## Abstract Loss‐of‐function mutations of the parkin gene causes an autosomal recessive juvenile‐onset form of Parkinson's disease (AR‐JP). Parkin was shown to function as a RING‐type E3 ubiquitin protein ligase. However, the function of parkin in neuronal cells remains elusive. Here, we show that