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Extracellular ATP and NADPH oxidase regulate plasma membrane calcium channels

✍ Scribed by Julia Davies


Book ID
113521403
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
71 KB
Volume
153
Category
Article
ISSN
1095-6433

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Extracellular ATP rendered the plasma membrane of transformed mouse fibroblasts permeable to normally impermeant molecules. This permeability change was prevented by increasing the ionic strength of the isotonic medium with NaCI. Conversely, the cells exhibited increased sensitivity to ATP when the