External irradiation of growth hormone producing pituitary adenomas: Prolactin as a marker of hypothalamic and pituitary effects
✍ Scribed by Eva af Trampe; Gr̈an Lundell; Ingmar Lax; Sigbritt Werner
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 657 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0360-3016
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## Background: It is well known that an unbalanced diet induces various changes in the pituitary gland. however, little attention has been paid to the molecular aspects of this perturbation. we studied the influence of a low-protein diet (lpd) on the prolactin (prl) and growth hormone (gh) cells in
Insulin and type I insulin-like growth factor (IGF-I) suppressed growth hormone (GH) expression followed by the induction of prolactin (PRL) biosynthesis in MtT/S cells cultured with normal sera. Insulin also increased the peptidylarginine deiminase activity in a dose-dependent manner. The increase