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Extent of polymerization in partially liganded sickle hemoglobin

โœ Scribed by Ling Ling Chung; Beatrice Magdoff-Fairchild


Book ID
115703723
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
392 KB
Volume
189
Category
Article
ISSN
0003-9861

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๐Ÿ“œ SIMILAR VOLUMES


Crowding and the polymerization of sickl
โœ Frank A. Ferrone; Maria A. Rotter ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 135 KB

## Abstract Under physiological conditions, sickle hemoglobin, a natural mutant of human hemoglobin A with a surface hydrophobic valine in place of a negatively charged glutamic acid, polymerizes at high volume occupancy. Equilibrium solubility of sickle hemoglobin entails activity coefficients tha