Extensive HLA class I allele promiscuity
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Nicole Frahm; Karina Yusim; Todd J. Suscovich; Sharon Adams; John Sidney; Peter
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Article
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2007
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John Wiley and Sons
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English
⚖ 360 KB
## Abstract Promiscuous binding of T helper epitopes to MHC class II molecules has been well established, but few examples of promiscuous class I‐restricted epitopes exist. To address the extent of promiscuity of HLA class I peptides, responses to 242 well‐defined viral epitopes were tested in 100