Extension of the Eschenmoser sulfide contraction/iminoester cyclization method to the synthesis of tolyporphin chromophore

✍ Scribed by Thomas G. Minehan; Yoshito Kishi

• Book ID: 104257929
• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 221 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)01601-8

✦ Synopsis

Tolyporphin chromophore 2 has been synthesized by performing a doubleretroaldol/oxidation sequence on an octahydroporphyrin precursor 18 prepared by using the Eschenmoser sulfide-contraction/iminoester-condensation method.