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Extension into the entrance channel of HIV-1 reverse transcriptase—Crystallography and enhanced solubility

✍ Scribed by Bollini, Mariela; Frey, Kathleen M.; Cisneros, José A.; Spasov, Krasimir A.; Das, Kalyan; Bauman, Joseph D.; Arnold, Eddy; Anderson, Karen S.; Jorgensen, William L.

Book ID
120531939
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
824 KB
Volume
23
Category
Article
ISSN
0960-894X

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Tests for the enzyme reverse transcriptase (RT) should permit the detection of all infectious retroviruses, provided that these are present as extracellular particles. The capability of a new procedure, named product-enhanced reverse transcriptase (PERT) assay, to detect HIV-1 in fresh human plasma