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Extending the substrate scope of a Baeyer–Villiger monooxygenase by multiple-site mutagenesis

✍ Scribed by Dudek, Hanna M.; Fink, Michael J.; Shivange, Amol V.; Dennig, Alexander; Mihovilovic, Marko D.; Schwaneberg, Ulrich; Fraaije, Marco W.


Book ID
121601527
Publisher
Springer
Year
2013
Tongue
English
Weight
537 KB
Volume
98
Category
Article
ISSN
1432-0614

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Stereoselective Desymmetrizations by Rec
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## Abstract In this work the substrate profile and stereoselectivity of engineered whole cells overexpressing the Baeyer–Villiger monooxygenase from __Xanthobacter__ sp. ZL5 with respect to biotransformations of prochiral substrates is characterized. This enzyme catalyzes the desymmetrization of cy