Paclitaxel is a recent chemotherapeutic agent that inhibits tubulin depolymerization in tumoral cells. Despite its increasing use against various human cancers, the genotoxicity of paclitaxel has never been studied on normal human cells. The in vitro genotoxic effects of the drug were evaluated with
Extended-term cultures of human T-lymphocytes and the comet assay: a useful combination when testing for genotoxicity in vitro?
✍ Scribed by Maria Andersson; Eva Agurell; Hamid Vaghef; George Bolcsfoldi; Björn Hellman
- Book ID
- 117767183
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 137 KB
- Volume
- 540
- Category
- Article
- ISSN
- 1383-5718
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