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Extended observations on MS patients treated with IM interferon-β1a (Avonex™): implications for modern MS trials and therapeutics

✍ Scribed by Lawrence Jacobs; Richard Rudick; Jack Simon


Book ID
114137128
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
82 KB
Volume
107
Category
Article
ISSN
0165-5728

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Extended observations on MS patients tre
✍ Lawrence Jacobs; Richard Rudick; Jack Simon 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 82 KB

Extended observations of the pivotal phase III clinical trial of interferon-beta1a (IFNbeta1a; Avonex, Biogen) in relapsing MS patients revealed that: (1) active treatment significantly slowed the accumulation of physical disability over time, reduced clinical exacerbations and MRI brain lesions; (2