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Extended blockade of the discriminative stimulus effects of nicotine with low doses of ethanol

✍ Scribed by Agnieszka Korkosz; Ewa Taracha; Adam Plaznik; Elzbieta Wrobel; Wojciech Kostowski; Przemyslaw Bienkowski

Book ID
113585337
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
136 KB
Volume
512
Category
Article
ISSN
0014-2999

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## Abstract The effect of different ligands for the GABA‐BZD receptor and the NMDA receptor were studied in rats trained to discriminate (βˆ’)‐nicotine (1.9 ΞΌmol/kg) from saline in a standard two‐bar operant conditioning paradigm with food reinforcement. MK‐801 (0.03–0.3 ΞΌmol/kg), flumazenil (10–30 ΞΌ