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Expression signatures that correlated with Gleason score and relapse in prostate cancer

โœ Scribed by Marina Bibikova; Eugene Chudin; Amir Arsanjani; Lixin Zhou; Eliza Wickham Garcia; Joshua Modder; Monica Kostelec; David Barker; Tracy Downs; Jian-Bing Fan; Jessica Wang-Rodriguez

Book ID
116981674
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
232 KB
Volume
89
Category
Article
ISSN
0888-7543

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Increase of AKT/PKB expression correlate
Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer
โœ Yongde Liao; Rainer Grobholz; Ulrich Abel; Lutz Trojan; Maurice Stephan Michel; ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 220 KB

AKT/PKB is a central signaling molecule related to stimulation of cell proliferation and inhibition of apoptosis. Perturbations of AKT expression and function play an important role in tumor development and progression. We wanted to determine (a) whether AKT is overexpressed in human prostatic tumor