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Expression, Purification and Functional Reconstitution of Slack Sodium-Activated Potassium Channels

✍ Scribed by Yan, Yangyang; Yang, Youshan; Bian, Shumin; Sigworth, Fred J.


Book ID
120377598
Publisher
Springer
Year
2012
Tongue
English
Weight
502 KB
Volume
245
Category
Article
ISSN
0022-2631

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Action potentials in mammalian nerve and muscle are generated by a stereotyped sequence of alterations in membrane conductance to monovalent cations [ 1,2]. The fundamental change that leads to the initiation of an action potential is a regenerative, but self-limited, increase in membrane conductanc