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Expression, Purification, and Characterization of Recombinant Purine Nucleoside Phosphorylase from Escherichia coli

โœ Scribed by John Lee; Serena Filosa; Julie Bonvin; Sebastien Guyon; Raphael A. Aponte; Joanne L. Turnbull


Book ID
115645850
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
136 KB
Volume
22
Category
Article
ISSN
1046-5928

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## Background: Previous studies have shown that herpes simplex virus thymidine kinase (hsv-tk)/ganciclovir (gcv) comprised the most commonly used suicide gene therapy for prostate cancer, with modest results being obtained. however, novel suicide genes, such as escherichia coli purine nucleoside ph