Expression profiling analysis of the CD5+ diffuse large B-cell lymphoma subgroup: Development of a CD5 signature
β Scribed by Miyuki Suguro; Hiroyuki Tagawa; Yoshitoyo Kagami; Masataka Okamoto; Koichi Ohshima; Hiroshi Shiku; Yasuo Morishima; Shigeo Nakamura; Masao Seto
- Book ID
- 108583704
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 311 KB
- Volume
- 97
- Category
- Article
- ISSN
- 1347-9032
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## Abstract The prognosis of diffuse large Bβcell lymphoma (DLBCL) has improved markedly in recent years of rituximab era. The prognosis of __de novo__ CD5βpositive DLBCL is reported to be poor, but the effect of rituximab on this type of lymphoma remains unclear. To investigate the effect of ritux
We recently demonstrated that the prognosis for de novo CD5-positive (CD5+) diffuse large-B-cell lymphoma (DLBCL) is markedly worse than that for CD5-negative (CD5-) DLBCL. Our findings also suggested that on the basis of its clinical features CD5+ DLBCL may constitute a unique disease category. How