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Expression profile and function of Wnt signaling mechanisms in malignant mesothelioma cells

✍ Scribed by Fox, Simon A.; Richards, Alex K.; Kusumah, Ivonne; Perumal, Vanathi; Bolitho, Erin M.; Mutsaers, Steven E.; Dharmarajan, Arun M.

Book ID
123293118
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
930 KB
Volume
440
Category
Article
ISSN
0006-291X

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## Abstract Malignant mesothelioma (MM) is an asbestos‐induced tumor that acquires aneuploid DNA content during the tumorigenic process. We used instable MM cell lines as an in vitro model to study the impact of DNA copy‐number changes on gene expression profiling, in the course of their chromosoma