Bone morphogenetic proteins (BMPs), a large subfamily of the transforming growth factor-beta (TGF-beta) superfamily of growth factors, have been implicated in patterning of the central nervous system, but their role in the retina is much less well known. As an initial step in addressing this issue,
Expression patterns of focal adhesion associated proteins in the developing retina
โ Scribed by Ming Li; Donald S. Sakaguchi
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 435 KB
- Volume
- 225
- Category
- Article
- ISSN
- 1058-8388
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Focal adhesion kinase (pp125FAK) has well-established functions in the attachment and growth of cells in culture and has been implicated as a marker of malignant progression in human tumors. To evaluate its role in the metastatic conversion of mouse skin tumors, pp125FAK activity and protein express
Hic-5 is a paxillin homologue with four LIM domains in its C-terminal region, localized mainly in focal adhesions in normal fibroblasts. Hic-5 is also known to associate with focal adhesion kinase (FAK) or the related CAKโค, and with vinculin. In the present study, we examined changes in Hic-5 and pa