Gap junctional intercellular communication (GJIC) has been proposed as a cellular mechanism for tumour suppression and there is experimental evidence in support of this. If aberrant GJIC contributes to the formation of human breast tumours, one might expect that the connexins (gap junction proteins)
β¦ LIBER β¦
Expression patterns of connexin 26 and connexin 43 mRNA in canine benign and malignant mammary tumours
β Scribed by Haruka Gotoh; Kayono Harada; Kazuyuki Suzuki; Shizu Hashimoto; Hozumi Yamamura; Tsuneo Sato; Keiko Fukumoto; Hiromi Hagiwara; Tatsuya Ishida; Kazuhiko Yamada; Ryuji Asano; Tomohiro Yano
- Book ID
- 113938604
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 99 KB
- Volume
- 172
- Category
- Article
- ISSN
- 1090-0233
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Connexin proteins form transmembranous gap junction channels that connect adjacent cells. Connexin26 and connexin30 have been previously shown to be strongly expressed in the inner ear of adult rats and to be mainly colocalized. Because intercellular connections by gap junction proteins are crucial