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Expression of β1, β3, β4, and β5 Integrins by Human Lung Carcinoma Cells of Different Histotypes

✍ Scribed by Rita Falcioni; Letizia Cimino; Maria Pia Gentileschi; Igea D'Agnano; Gabriella Zupi; Stephen J. Kennel; Ada Sacchi


Book ID
115601634
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
672 KB
Volume
210
Category
Article
ISSN
0014-4827

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Cytofluorimetric and reverse-transcription polymerase chain reaction (RT-PCR) analysis showed that adriamycinresistant (ADR R ), but not sensitive (WT), MCF-7 human mammary carcinoma cell lines express a4b1 and a5b1 integrins. ADR R cells adhere to fibronectin (FN), and only a5b1 is involved in cell