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Expression of α5β1 and α6β1 integrins in IgA nephropathy (IgAN) with mild and severe proteinuria. An immunohistochemical study

✍ Scribed by Małgorzata Wągrowska-Danilewicz; Marian Danilewicz

Book ID: 111614421
Publisher: Springer Netherlands
Year: 2004
Tongue: English
Weight: 209 KB
Volume: 36
Category: Article
ISSN: 0301-1623
DOI: 10.1023/b:urol.0000032707.22306.d1

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## Abstract Mice lacking the α6 integrin chain die at birth with severe skin blistering. To further study the function of α6 integrin in skin, we generated conditionally immortalized cell lines from the epidermis of wild‐type and α6 deficient mouse embryos. Mutant cells presented a decreased adhesi