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Expression of α2,8-sialyltransferase (GD3 synthase) gene in human cancer cell lines: high level expression in melanomas and up-regulation in activated T lymphocytes

✍ Scribed by Shuji Yamashiro; Masahiko Okada; Masashi Haraguchi; Keiko Furukawa; Kenneth O. Lloyd; Hiroshi Shiku; Koichi Furukawa

Publisher
Springer US
Year
1995
Tongue
English
Weight
810 KB
Volume
12
Category
Article
ISSN
1573-4986

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## Abstract Gangliosides are sialic acid–containing glycosphingolipids that are associated with tumor malignancy and progression. Among the enzymes required for the production of gangliosides, sialyltransferases have received much attention in terms of their relationship with cancer. In our previou