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Expression of vascular endothelial growth factor and transcription factors HIF-1, NF-kB expression in squamous cell carcinoma of head and neck; association with proteasome and calpain activities

โœ Scribed by Spirina, Liudmila V.; Kondakova, Irina V.; Choynzonov, Evgeny L.; Chigevskaya, Svetlana Y.; Shishkin, Dmitry A.; Kulbakin, Denis Y.


Book ID
118241632
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
388 KB
Volume
139
Category
Article
ISSN
1432-1335

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## Abstract ## Background and Methods. VEGF proteins and their receptors are involved in tumor vessel neoformation. The third VEGF receptor, VEGFR3 (fltโ€4) is important during both blood vessel development and lymphatic vessel formation. Because HNSCC preferentially metastasizes to regional lymph