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Expression of vascular endothelial growth factor and its receptor Flk-1 in human neuroblastoma using in situ hybridization

✍ Scribed by Masahiro Fukuzawa; Hiroaki Sugiura; Tsugumichi Koshinaga; Taro Ikeda; Noritugu Hagiwara; Tatsuo Sawada

Book ID
117827748
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
150 KB
Volume
37
Category
Article
ISSN
0022-3468

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Background. Vascular endothelial growth factor (VEGF) is a specific endothelial cell mitogen that stimulates angiogenesis and plays a crucial role in tumor growth. The aim of the present study was to evaluate the expression of VEGF and of its two high-affinity tyrosine kinase receptors (KDR and Flt-