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Expression of Vascular Endothelial Growth Factor-A, Matrix Metalloproteinase-9, and Extravascular Matrix Patterns and Their Correlations with Clinicopathologic Parameters in Posterior Uveal Melanomas

โœ Scribed by Afsun Sahin; Hayyam Kiratli; Figen Soylemezoglu; Gaye Guler Tezel; Sevgul Bilgic; Osman Saracbasi


Publisher
Springer
Year
2007
Tongue
English
Weight
389 KB
Volume
51
Category
Article
ISSN
0021-5155

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Vascular endothelial growth factor expre
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Vascular endothelial growth factor (VEGF) is the major endothelial mitogen in central nervous system neoplasms and it is expressed in 64-95% of glioblastomas (GBMs). Tumour cells are the main source of VEGF in GBMs whereas VEGF receptors (VEGFR-1, its soluble form sVEGFR-1, VEGFR-2 and neuropilin-1)