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Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy

✍ Scribed by Yoshinori Seko; Shigeru Ishiyama; Toshiro Nishikawa; Takeshi Kasajima; Michiaki Hiroe; Shin Suzuki; Sugao Ishiwata; Sachio Kawai; Yuetsu Tanaka; Miyuki Azuma; Tetsuji Kobata; Hideo Yagita; Ko Okumura; Ryozo Nagai

Book ID: 117713348
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 152 KB
Volume: 11
Category: Article
ISSN: 1054-8807
DOI: 10.1016/s1054-8807(02)00101-1

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T-cell-mediated myocardial damage has been shown to be involved in acute myocarditis and dilated cardiomyopathy. It is necessary for T-cells to receive a co-stimulatory signal as well as the main signal through the T-cell receptor for antigen-specific T-cell activation to occur. To investigate the r