Expression of transforming growth factor-α and epidermal growth factor receptor in gastrointestinal stromal tumours
✍ Scribed by Yun-Cai Cai; Zhong Jiang; Frank Vittimberga; Xiaowen Xu; L. Savas; Bruce Woda; Mark Callery; B. Banner
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 267 KB
- Volume
- 435
- Category
- Article
- ISSN
- 1432-2307
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Epidermal growth factor (EGF) and transforming growth factor-~ (TGF-~) are polypeptides which bind to the EGF receptor (EGFr) and may play a role in cell growth and carcinogenesis. Our study investigated the content of EGF, TGF<z, and EGFr in tumors of the stomach and the colon in comparison with th
We have investigated the actions of transforming growth factor (TGF) type a on epidermal growth factor (EGF) receptor mRNA expression in MDA-468 human mammary carcinoma cells in serum-free media. We found that exposure of MDA-468 cells to TGFa results in elevated levels of EGF receptor mRNA. This in
Transforming growth factor-alpha (TGF␣) is an epidermal growth factor receptor (EGFR) ligand which is distinguished from EGF by its acid-labile structure and potent transforming function. We recently reported that TGF␣ induces less efficient EGFR heterodimerization and downregulation than does EGF (