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Expression of tissue factor and tissue factor pathway inhibitor in porcine endothelium in response to natural antibody and complement

โœ Scribed by T Nagayasu; S Saadi; R.A Holzknecht; Y Miyata; T.B Plummer; J.L Platt


Book ID
117230307
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
59 KB
Volume
33
Category
Article
ISSN
0041-1345

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Tissue factor (TF) initiates the extrinsic pathway of blood coagulation by acting as a cofactor for Factor VII. Inhibition of the Factor VIIa-TF complex is mediated by the tissue factor pathway inhibitor (TFPI), which is a serine protease inhibitor with three Kunitz-type domains. The localization of